tau protein aggregation-in-1 — TargetMol Chemicals

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Search Results for " tau protein aggregation-in-1 "

Compounds

Cat No.	Product Name	Targets
T79038	Tau protein aggregation-IN-1
	Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders including Alzheimer's disease, dementia, Parkinson's disease, Hunt...
T62899	Tau-aggregation and neuroinflammation-IN-1	Microtubule Associated , NO Synthase
	Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. Tau-aggregation and neuroinflamma...	Microtubule Associated , NO Synthase
T63481	Tau-aggregation-IN-1
	Tau-aggregation-IN-1 is a dopamine D2 and D3 receptor agonist and an inhibitor of tau441 protein aggregation (IC50: 21 μM).
T78173	Aβ/tau aggregation-IN-3
	Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. This compound demonstrates anti-amyloid activ...
T61579	BuChE-IN-5
	BuChE-IN-5 (compound 25b) is a highly potent BuChE inhibitor, displaying an IC50 value of 1.94 μM. It effectively inhibits aggregation of Aβ and tau protein in Escherichia coli. Furthermore, BuChE-IN-5 exhibits considera...
T74812	HBChE-IN-1
	hBChE-IN-1 (compound 4), a quinolizidinyl derivative, effectively inhibits human Butyrylcholinesterase (hBChE) with an IC50 value of 7 nM, demonstrating high selectivity against human Acetylcholinesterase (hAChE). It als...
T82242	HAChE-IN-6
	hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM. It also demonstrates inhibitory effects on human butyrylcholinesterase (hBuChE) and glycogen synthase kin...
T82243	HAChE-IN-5	GSK-3
	hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency with IC50 values of 0.17 μM for both enzymes. Additionally, it de...	GSK-3
T75339	Methylene blue hydrate
	Methylene Blue (Basic Blue 9) hydrate functions as an inhibitor of guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS). This compound, known for its vasopressor activity, is widely utilized as a dy...